I am not entirely sure I understand what you are after, but I have written large worksheets which are essentially papers (actually, more like text-book chapters).
First, I learned the hard way not to make a sheet too long. At least in older Maple versions, sheets exceeding a few MB in size cause trouble with Maple becoming intolerably slow. So I structure thing such that I don't need excessively long sheets.
In a sheet, I use sections, but not excessively so. Maybe 3 or 4 per sheet. They can nest if desired.
I do make extensive use of equation numbers (labels) when I reference prior results. I like Maple's way of structured labels (section.subsection.eqationnumber). Maple handles the renumbering well (by and large) when I need to insert stuff at an earlier location in the sheet.
I rarely, if ever, use ":" to suppress output.
I do bundle some often-used routines in a Package. For actual work (as opposed for writing something more like a paper) I have some very large Packages that are well structured and documented and make full use of Maples object-orientation-like features (i.e. modules containing modules containing records and procs) I have found this very powerful for large programs, although less so for writing papers.
I can and do work with such sheets on a 13-inch screen esp. when on travel even if I prefer the larger screens I have @ home and @ work.
I hope this helps,